Understanding Age-Related Macular Degeneration and AREDS2 Supplements
Age-related macular degeneration (AMD) leads to gradual vision loss. While it can’t be cured, there are ways to slow the disease’s progression, such as through the use of AREDS2 supplements.
Ophthalmologist Kevin Keppel, MD explains how these supplements work, their ingredients, and the long-term expectations for vision.
What is AREDS2?
AREDS2 supplements are designed for individuals diagnosed with intermediate or advanced AMD. They contain a specific blend of vitamins and minerals that may help in slowing the progression of the disease.
“AREDS2 can slow the progression of the disease before it becomes more severe,” says Dr. Keppel. The original Age-Related Eye Disease Study (AREDS) established the effectiveness of high levels of antioxidants and zinc in reducing the risk of advanced AMD. The subsequent AREDS2 trial emphasized the benefits of adding lutein and zeaxanthin.
AREDS2 Formula
The AREDS2 formula consists of:
- 500 mg of Vitamin C
- 400 IU of Vitamin E
- 2 mg of Copper
- 10 mg of Lutein
- 2 mg of Zeaxanthin
- 80 mg of Zinc
These components primarily act as antioxidants, protecting the retina from damage associated with AMD.
Benefits of AREDS2
AREDS2 supplements are designed to:
- Reduce progression from intermediate to advanced AMD.
- Lower the risk of significant central vision loss.
- Help preserve vision longer.
- Support overall retinal health.
Dr. Keppel emphasizes that AREDS2 is a long-term protective supplement that can lower the risk of future vision loss.
Potential Risks
Some mild digestive side effects may occur when taking AREDS2, including:
- Stomach cramps
- Nausea
- Changes in bowel movements
There may also be rare risks, especially with high amounts of zinc and vitamin E. It’s essential to discuss with a primary care physician if the individual is on medications such as blood thinners.
AREDS vs. AREDS2
While the original AREDS formula is available, it may not be suitable for individuals who smoke, as it has been linked to an increased risk of lung cancer. Dr. Keppel recommends the AREDS2 formula for its enhanced safety and efficacy.
Conclusion
AREDS2 has been shown to reduce the risk of progressing from intermediate AMD to advanced AMD by about 25%, offering hope for those affected as they age. Regular eye exams after age 50 are crucial for monitoring AMD and assessing the need for supplements like AREDS2.
