Categories Wellness-Health

Nutra Research Round-Up: Vitamin D, Postbiotics, HMB Protein, and NMN

Recent Studies on Nutritional Supplements and Health Benefits

Various studies have explored the impact of nutritional supplements on health, revealing promising results. This article delves into recent findings regarding vitamin D, oral health, cholesterol management, and other supplements that have shown beneficial effects in different populations.

Doses of 600-800IU vitamin D were consistently associated with attaining sufficiency

Doses of 600-800IU vitamin D were consistently associated with attaining sufficiency (jarun011/Getty Images)

A recent study indicates that daily supplementation of vitamin D3, at doses between 400–800 IU in the form of a chocolate wafer over 12 weeks, significantly increased serum 25(OH)D levels among vitamin D-deficient young women in India.

While the 400 IU daily dosage effectively eliminated deficiency, higher doses of 600-800 IU were found to be more consistently linked to achieving sufficiency. Notably, 65.4% of participants receiving 800 IU daily restored their levels by the end of the 12-week period.

“In this context, serum 25(OH)D serves as a robust biochemical marker of vitamin D status, reflecting the cumulative effects of dietary intake and endogenous synthesis,” the researchers stated in the journal Nutrients.

Gingivitis is the inflammation of the gums and occurs when microbial plaque accumulates on the tooth surface due to ineffective tooth brushing.

Gingivitis is the inflammation of the gums and occurs when microbial plaque accumulates on the tooth surface due to ineffective tooth brushing. (Daria Kulkova/Getty Images)

Another study conducted in Japan showed that supplementation with heat-inactivated Lactiplantibacillus pentosus ONRICb0240 positively impacted aspects of oral health, particularly in reducing gingival inflammation.

Significant improvements were observed in the bleeding on probing percentage (BOP), which is a commonly used criterion for diagnosing gingival inflammation, as noted by researchers in the Journal of Periodontology.

Additionally, noteworthy improvements in the Gingival Index (GI), a scale that assesses the degree of gingival inflammation through visual evaluation of redness and swelling, were reported.

A new study from China reported that supplementation of B. breve BBr60 probiotics could lower cholesterol levels.

A new study from China reported that supplementation of B. breve BBr60 probiotics could lower cholesterol levels. (AlexeyBlogoodf/Getty Images)

In a separate study conducted in Thailand, daily supplementation of beta-glucans, specifically either β-1,3/1,6-glucan oligosaccharides or polysaccharides, led to a significant reduction in total cholesterol levels over a period of 12 weeks.

Two weeks after completing the supplementation, cholesterol levels remained significantly lower than baseline in the oligosaccharide group, indicating a more lasting effect. Researchers reported these findings in Food Science and Nutrition.

Moreover, low-density lipoprotein (LDL) levels saw a marked reduction in the oligosaccharide group after 12 weeks, with the effects still present two weeks after intervention; this outcome was not observed in the polysaccharide group.

HMB protein supplementation could improve functional outcomes such as walking distance and chair rises in sarcopenic surgical patients, despite no gains in muscle quality, says a new pilot study by Abbott Nutrition.

HMB protein supplementation could improve functional outcomes such as walking distance and chair rises in sarcopenic surgical patients, despite no gains in muscle quality, says a new pilot study by Abbott Nutrition. (manassanant pamai/Getty Images)

In another study, a high-protein beta-hydroxy beta-methylbutyrate (HMB) supplement, alongside physical exercise, was found to enhance functional outcomes in sarcopenic surgical patients over a six-month period.

Researchers highlighted in Nutrients that this supplementation significantly improved chair rise repetitions and performance in the six-minute walk test at six months following gastrointestinal surgery.

Moreover, various anthropometric measurements, including mid-arm muscle circumference, mid-arm muscle area, weight, and body mass index, also showed significant increases six months post-operation.

Nicotinamide mononucleotide supplement, niacin, anti-aging vitamin. White pills forming shape to NMN letters on yellow background, copy space, top view.

NMN (beta-nicotinamide mononucleotide) is one of the forms of vitamin B3, or niacin (Mizina/Getty Images)

Lastly, a pilot study in Taiwan examined the effects of nicotinamide mononucleotide (NMN) supplementation on inflammation in young men who underwent blood flow restriction-resistance training.

Results indicated a significant reduction in inflammatory cytokine mRNA expression, including TNF-α, in skeletal muscle post-exercise following NMN supplementation. Researchers recognized this as the first human study documenting such findings in the Journal of the International Society of Sports Nutrition.

In conclusion, these diverse studies highlight the potential health benefits from various nutritional supplements, ranging from improved vitamin D levels to enhanced oral health and effective management of cholesterol. The findings underscore the importance of continued research and consideration of these supplements in health and wellness strategies.

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