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Unity and AMILI Introduce Synbiotics Inspired by the Asian Gut Microbiome

AMILI Metabolic Health Launch and Research

Product Availability
AMILI Metabolic Health is set for exclusive retail availability via Unity starting September 2026, following its initial release in selected practitioner channels.

Formulation Background
The product’s unique formulation is grounded in Asian gut microbiome data, particularly from Singapore’s National University Hospital (NUH) and AMILI’s multi-ethnic Asian Microbiome Library, which includes data from both patients with conditions like hypertension and hyperlipidemia, and healthy individuals participating in AMILI’s gut microbiome tests.

Asian Gut Microbiome Insights
Dr. Jeremy Lim, co-founder and CEO of AMILI, emphasizes the significance of utilizing Asian-specific microbiome data, stating, “An Asian gut is not the same as a Western one.” The product aims to improve the health of Singaporeans and highlights the influence of diet, lifestyle, and environment on gut health.

Innovative Synbiotic
Pauline Png, general manager at Unity, points out that this synbiotic is the first of its kind available across Unity stores, addressing the lesser-known benefits of synbiotics for metabolic health.

Research and Development
The R&D process employs both patient and healthy individual microbiome data for comprehensive analysis. Key comparisons focus on the diversity of microbes between populations and their metabolic interactions.

The formulation includes four probiotic strains:

  • Lactobacillus rhamnosus: Improves fasting blood glucose and liver function.
  • Bifidobacterium animalis subsp. lactis
  • Lactobacillus plantarum
  • Bifidobacterium adolescentis

Postbiotics and Prebiotics
It also features Akkermansia (a postbiotic), prebiotic fibers, and botanical extracts such as milk thistle. An AI model helped determine the optimal dosages and proportions of the probiotic strains used.

Validation and Efficacy
The formulation was validated against clinical endpoints, focusing on glycemic, lipid, and hepatic health markers, utilizing AMILI’s functional microbiota assay with Asian stool donors.

Focus on Metabolic Health

Rising Health Challenges
Metabolic health was targeted due to its prevalence as a health challenge in Asia. Dr. Lim notes that in accordance with World Health Organization guidelines, Asian BMI thresholds for obesity are lower than those for Western populations.

Health Statistics
Singapore’s health landscape reflects concerns over chronic conditions, with obesity rates climbing and significant proportions of residents experiencing high cholesterol and blood pressure.

Conclusion
As metabolic conditions rise, understanding the gut microbiome’s role becomes crucial for developing tailored health solutions, bringing together clinical and microbiome science insights for effective health interventions in Asian populations.

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