Recent research published in Science Advances indicates that while a ketogenic diet can result in weight loss, it may also lead to metabolic complications that could contribute to heart disease and other serious health issues.
The study conducted a long-term examination involving adult mice assigned to one of four dietary regimens for nine months or longer. The diets included a high-fat regimen designed to replicate a typical Western diet, a traditional ketogenic diet, a low-fat high-carbohydrate diet, and a protein-matched low-fat diet. Throughout the experiment, researchers monitored body weight and food intake. They also assessed various metabolic health indicators, such as blood lipid levels, liver fat accumulation, blood sugar, and insulin levels. While ketogenic diets—which are characterized by high fat intake and minimal carbohydrates—are often adopted for weight loss and managing type 2 diabetes, their long-term effects remain inadequately studied. This investigation aimed to uncover the potential long-term health impacts of ketogenic diets.
Results indicated that the ketogenic diet successfully prevented weight gain in the mice, particularly in comparison to those on the Western diet. However, mice on the ketogenic regimen exhibited a significantly higher likelihood of developing metabolic issues, including fatty liver disease, disruptions in blood sugar levels, and difficulties with blood sugar regulation. If left unaddressed, these metabolic concerns could escalate into more severe health problems, such as heart disease and diabetes.
The study’s authors emphasized that individuals contemplating a ketogenic diet should thoroughly weigh the potential benefits against the associated risks, especially if they intend to maintain the diet long-term. Consulting with healthcare professionals before making any dietary changes is highly advisable. Although dietary modifications may appear harmless, they can introduce significant long-term health risks if not evaluated and monitored correctly.
Sources: Science Advances, Science Daily
