About the Experts
|
Recently, social media has seen a surge in discussions about the “cortisol cocktail”—a refreshing citrus drink that claims to enhance energy, alleviate stress, and promote hormonal balance. Given today’s hectic lifestyle, where 77% of people feel that stress adversely affects their physical health, and 73% report a negative impact on mental well-being, it’s understandable that many are seeking simple ways to find relief.
Cortisol, often referred to as the stress hormone, is released by the adrenal glands during moments of stress. It plays a vital role in regulating metabolism, managing inflammation, controlling blood pressure, and governing our sleep-wake cycles. Fluctuations in cortisol levels can lead to noticeable changes in mood, energy, and overall health.
But does this homemade “cortisol cocktail” really have the desired effects? With a background in family medicine and national certification in nutrition, I decided to test this trendy drink for a week—especially with my wedding just around the corner. I also consulted Julia Zumpano for expert advice on maximizing the drink’s benefits and exploring other ways to achieve similar results.
What Is the “Cortisol Cocktail”?

The cortisol cocktail, sometimes called the “adrenal cocktail,” evokes a sense of relaxation and wellness. This naturally vibrant drink is promoted for its potential to support adrenal health, replenish essential nutrients, and help regulate cortisol production.
Though various powdered mixes are commercially available, Zumpano recommends creating this drink at home. A traditional cortisol cocktail should consist of:
- Half a cup of orange juice, abundant in vitamin C (supporting adrenal function) and potassium—opt for pure orange juice with minimal added sugars or artificial flavors.
- Half a cup of coconut water, a natural source of electrolytes.
- A pinch of sea salt, contributing sodium and trace minerals.
This blend contains approximately:
- 80 calories
- 17 grams of carbohydrates
- 130 milligrams (mg) of sodium
- 550 mg of potassium
Zumpano mentioned that the nutritional values may vary depending on optional add-ins. Some individuals incorporate ingredients like collagen protein powder, cream of tartar (adding extra potassium), or coconut cream to enhance the nutrient content.
Before making my own cortisol cocktail, I consulted Zumpano about healthy preparation methods. She advised, “Limit it to eight ounces maximum. Adding collagen protein or coconut cream can help regulate blood sugar spikes by slowing sugar absorption.” She also cautioned against excessive salt intake, particularly for those on sodium-restricted diets.
Potential Benefits and Precautions of a Cortisol Cocktail
Proponents of the cortisol cocktail claim it can:
- Enhance energy levels
- Rehydrate and replenish electrolytes
- Support hormonal balance
- Alleviate stress and fatigue
- Improve sleep quality
A widely discussed benefit is its potential to combat adrenal fatigue. However, current medical literature fails to support this claim. The adrenal glands, located above each kidney, produce cortisol among other hormones. Some theorize that chronic stress may “deplete” the adrenals, resulting in fatigue and hormonal imbalances.
Dr. Pratibha Rao, an endocrinologist at the Cleveland Clinic, states, “In medicine, our practice is based on evidence, and there is no credible data confirming that adrenal fatigue exists,” as she noted in the Clinic’s Health Essentials blog.
Moreover, there is no solid proof that cortisol cocktails directly nourish or support adrenal glands beyond what a balanced diet can provide. That said, Dr. Rao mentions that they are generally safe for most individuals, provided they don’t overconsume and lack underlying health conditions.
It’s essential to distinguish between adrenal fatigue and adrenal insufficiency, a serious medical condition where the adrenal glands do not produce adequate cortisol. Symptoms include nausea, vomiting, low blood pressure and sugar levels, and extreme fatigue. If these signs are present, consulting a healthcare provider is crucial.
My Experience: Drinking a Cortisol Cocktail Every Day
For a week, I drank a cortisol cocktail each afternoon around 3 p.m.—a time when my energy usually dropped, prompting cravings for caffeine or sugary snacks. I stuck to the basic recipe: half a cup of orange juice, half a cup of coconut water, and a pinch of pink Himalayan salt. On some days, I added coconut cream to support blood sugar stability.
Here’s what I observed—both positive aspects and shortcomings:
Enjoyment of Drinking a Cortisol Cocktail
The most delightful aspect of consuming a cortisol cocktail was its refreshing nature, especially during the warm Florida afternoons. It provided a hydrating alternative to plain water, and I relished the zesty flavor.
“Sodium and potassium are essential minerals (and electrolytes) for cellular function and fluid balance,” explains Zumpano. “You need about twice as much potassium as sodium,” which this drink provides.
Beyond taste, I felt more hydrated. One effective way to gauge hydration levels is through urine color—a pale yellow indicates good hydration, while a darker shade can signify dehydration. Throughout the week, my urine remained consistently light yellow, suggesting the cocktail’s electrolytes were working effectively. I also noted fewer signs of dehydration, such as dry mouth or that common afternoon fatigue. Furthermore, consuming a cortisol cocktail could serve as a healthier alternative to artificially flavored sports drinks, offering natural hydration without added sugars or synthetic additives.
Energy Boost from Drinking a Cortisol Cocktail
Reducing caffeine intake has been a personal goal of mine, and during the week I opted for the cortisol cocktail, I successfully refrained from coffee. While I made a concerted effort to hydrate and eat nutrient-dense foods, I still experienced a consistent midday energy uplift following the cocktail.
The natural sugars from the orange juice delivered a quick energy boost, while the electrolytes from the coconut water and sea salt likely assisted with hydration, helping alleviate that afternoon slump. Dr. Rao notes that hydration and a balanced diet are crucial for maintaining energy, and one doesn’t necessarily need a cortisol cocktail for that.
A Cortisol Cocktail Is Not a Stress Remedy
Despite various online assertions that cortisol cocktails can alleviate stress, there’s currently no scientific backing to confirm that consuming this cocktail reduces cortisol levels or soothes the body’s stress response.
Though refreshing and enjoyable, the cocktail did not erase my stress. While it provided a relaxing interlude in my afternoon and helped keep me hydrated, I did not notice any significant changes in my reactions to daily stressors.
For those seeking proven methods to manage stress, many medical professionals recommend focusing on:
- Regular exercise: Physical activity effectively reduces cortisol levels and releases mood-enhancing endorphins. Even simple brisk walking can make a difference.
- Getting adequate sleep: Insufficient sleep is closely tied to elevated cortisol levels and increased stress sensitivity.
- Practicing mindfulness or meditation: Research shows that mindfulness-based stress reduction (MBSR) techniques can significantly lower cortisol and perceived stress.
- Building social connections: A strong support network is associated with lower stress hormone levels and improved mental health.
- Limiting caffeine and alcohol: Overuse of these substances can disrupt the body’s natural stress response.
- Maintaining a balanced diet: Nutrient-rich foods help maintain hormonal balance and support mood regulation.
Will I Continue Drinking Cortisol Cocktails?
While I don’t anticipate making a cortisol cocktail part of my daily routine, I can see it becoming an occasional treat for hydration. The combination of vitamin C, potassium, and electrolytes offers notable benefits; however, other dietary sources can provide those nutrients just as well.
When I asked Zumpano for more sustainable ways to obtain the same benefits through food, she suggested several potassium-rich options, such as:
- Bananas
- Oranges
- Potatoes
- Cantaloupe
- Avocados
- Leafy greens
- Broccoli
- Sweet potatoes
- Beets
- Honeydew melon
Vitamin C-rich foods include:
- Citrus fruits
- Bell peppers
- Strawberries
- Kiwi
- Papaya
- Broccoli
- Brussels sprouts
- Tomatoes
- Kale
Regarding the sodium in the cocktail, Zumpano remarked, “Most people consume adequate, if not excessive, sodium through the Standard American Diet (SAD). Extra sodium is generally unnecessary unless on a whole foods diet and requiring added salt to meet nutritional needs.”
In summary, if you maintain a balanced diet rich in whole fruits and vegetables, you are likely already obtaining the nutrients that a cortisol cocktail offers, negating the need for a daily drink.
Are There Side Effects to Drinking Cortisol Cocktails?
While a cortisol cocktail can serve as a hydrating and nutrient-rich choice for many, it does have potential downsides, especially if consumed excessively. Possible side effects include:
- Blood sugar spikes, particularly for those with diabetes or insulin resistance, due to the natural sugars in orange juice.
- Increased blood pressure, as added sea salt raises sodium intake.
- Electrolyte imbalances, especially in individuals with kidney problems, if consumed in excess.
- Tooth enamel erosion, as acidic citrus juices can wear down enamel over time without proper dental hygiene.
Are Cortisol Cocktails Safe for Everyone?
For most healthy individuals, drinking a cortisol cocktail daily is generally considered safe, according to Zumpano. However, those with underlying health conditions should approach with caution. The ingredients—especially potassium from coconut water and sodium from salt—might pose risks for certain populations.
Consult your doctor before incorporating a daily cortisol cocktail if you have:
- Kidney disease
- High blood pressure
- Diabetes or insulin resistance
- Heart conditions requiring fluid restrictions
For regular health updates, consider subscribing to The Healthy by Reader’s Digest newsletter, and be sure to follow The Healthy on Facebook and Instagram. Explore further: