Maximize Energy, Metabolism, and Longevity with NAD Supplements: Expert Tips

The rise of anti-aging solutions is becoming increasingly evident as more individuals seek ways to maintain their vitality and youthfulness. In this landscape, peptides have gained attention, prompting many to move away from intense HIIT workouts in favor of exercises designed to enhance longevity. Traditional supplements like vitamin D and magnesium are now stepping aside for innovative products promising increased healthspan, particularly NAD—a multifunctional molecule that researchers assert can improve DNA health and boost everything from energy to skin health.

So, what exactly is NAD, and should you consider its benefits? In an era where social media influencers are experimenting with substances like retatrutide even before clinical trials conclude, it’s crucial to scrutinize not just the effectiveness but also the safety of the emerging supplements and drugs inundating our feeds.

Here’s what experts and peer-reviewed clinical research reveal about NAD.

What is NAD?

NAD stands for nicotinamide adenine dinucleotide, a molecule essential for various vital functions in the body. According to Emma Wedgwood, an advanced nurse practitioner, it primarily “helps keep our cells functioning properly.”

“NAD plays a crucial role in energy production by converting the food we consume into the fuel our cells require,” adds Wedgwood. “It exists in two forms, NAD+ and NADH, which collaborate to ensure our bodies have sufficient energy for essential functions. Besides energy production, NAD supports processes such as DNA repair and immune health. As we age, our levels of NAD+ tend to decrease, influencing energy, cell regeneration, and becoming a focal point in anti-aging and wellness research.”

This makes NAD a popular choice for health supplements, particularly among those over 30 experiencing declines in energy, metabolism, and immune support.

Is there a difference between NAD+ and NADH?

You might encounter both NAD+ and NADH in supplement offerings. The distinction between the two lies in their roles within the body, according to Wedgwood.

“NAD+ is responsible for creating energy by converting food into fuel and supporting cell repair. It serves as the ‘starter’ for energy production,” explains Wedgwood. “In contrast, NADH is the form that carries and delivers energy where it’s needed in the body. Think of NAD+ as the producer of energy, while NADH acts as the transporter, ensuring that cells receive the energy they require. Both forms work in tandem to keep everything operating smoothly.”

What are the benefits of NAD?

Due to its crucial role in DNA function, NAD serves a plethora of beneficial functions in the body, with highlights including enhanced energy levels, metabolic support, skin health, immune system support, and DNA repair.

How does it achieve these benefits? Dr. Rishi Mandavia, managing director at Doctors Tatiana + Rishi Advanced Aesthetics, states that it revolves around energy conversion. “NAD significantly impacts your metabolism, which is the process your body uses to transform food into energy. It assists in critical processes that yield ATP [adenosine triphosphate], the energy currency your cells need to operate. If NAD levels are insufficient, your body’s ability to produce energy diminishes, complicating your metabolic functions.”

NAD also offers anti-aging benefits. “It is associated with anti-aging because it aids in cell repair, protects against damage, and supports healthy functions such as DNA repair and mitochondrial health,” emphasizes Mandavia. “As NAD+ levels naturally decline with age, maintaining higher levels may help mitigate some signs of aging—though further research is necessary.”

Moreover, NAD can influence “stress management, immune function, and the regulation of your internal clock or circadian rhythms,” adds Mandavia. “It also plays a role in gene expression, which can affect overall health and longevity.”

Can you take a NAD supplement?

This is where things become slightly more intricate. NAD supplements can be ingested in either oral forms (typically tablets or powders) or delivered via intravenous or intramuscular injections. The correct supplementation is associated with benefits including increased energy levels, enhanced metabolism, improved stress management, and even better sleep, among other advantages.